Attenuation of fungal virulence by synthetic infectious mycoviru

Chemistry: molecular biology and microbiology – Treatment of micro-organisms or enzymes with electrical or... – Cell membrane or cell surface is target

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4351721, 43525411, 4352568, 935 52, C12N 1300

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active

056655819

ABSTRACT:
This invention is directed to naturally virulent fungi which have cells transfected with the coding strand of a mycovirus RNA and which have reduced ability to cause disease in plants, and to compositions and methods of treatment of fungal disease with these fungi.

REFERENCES:
GC Ainsworth (1971) Dictionary of the Fungi p. 140.
GH Choi et al (1992) Science 257:800-803.
RA Jaynes et al (1980) Phytopathology 70:453-456.
BI Hillman et al (1990) Phytopathology 80:950-956.
AL Shigo (1984) Ann Rev Phytopathiol 22:189-214.
Turchetti et al., "Mixed inoculum for the biological control of chestnut blight", Bulletin OEPP/EPPO, 18:67-72 (1988).
Turchetti and Maresi, "Inocultion trials with hypovirulent strains of Cryphonectria parasitica", Eur. J. For. Path., 21:65-70 (1991).
Anagnostakis, "Improved chestnut tree condition maintained in two Connecticut plots after treatments with hypovirulent strains of the chestnut blight fungus", Forest Science 36:113-124 (1990).
Shapira et al., "Virus-like genetic organization and expression strategy for a double-stranded RNA genetic element associated with biological control of chestnut blight", EMBO J. 10:731-739 (1991).
Choi and Nuss, "A viral gene confers hypovirulence-associated traits to the chestnut blight fungus", EMBO J. 11:473-477 (1992).
Choi et al., "Cotranslational autoproteolysis involved in gene expression from a double-stranded RNA genetic element associated with hypovirulence of the chestnut blight fungus", PNAS (USA) 88:1167-1171 (1991).
Choi et al., "The autocatalytic protease p29 encoded by a hypovirulence-associated virus of the chestnut blight fungus resembles the potyvirus-encoded protease HC-Pro", Virology 183:747-752 (1991).
Shapira and Nuss, "Gene expression by a hypovirulence-associated virus of the chestnut blight fungus involved tow papain-like protease activities", J. Biolog. Chem., 266:19419-19425 (1991).
Koonin et al., "Evidence for common ancestry of a chestnut blight hypovirulence-associated double-stranded RNA and a group of positive-strand RNA plant viruses", PNAS (USA) 88:10647-10651 (1991).
Nuss et al., "Significance of dsRNA genetic elements in plant pathogenic fungi", Annu. Rev. Phytopathol. 28:37-58 (1990).
Shapira et al., "The contribution of defective RNAs to the complexity of viral-encoded double-stranded RNA populations present in hypovirulent strains of the chestnut blight fungus Cryphonectria parasitica", The EMBO J. 10:741-746 (1991).
Van Alfen, "Biology and potential for disease control of hypovirulence of Endothia parasitica", Annu. Rev. Phytopathol 20:349-362 (1982).
Rae et al., "Characterization of double-stranded RNA genetic elements associated with biological control of chestnut blight: organization of terminal domains and identification of gene products", EMBO J. 8:657-663 (1989).
Hillman et al., "Hypovirulence-associated suppression of host functions in Cryphonectria parasitica can be partially relieved by high light intensity", Phytopathology 80:950-956 (1990).
Boyer and Haenni, "Infectious transcripts and cDNA clones of RNA viruses", Virology 198:415-426 (1994).
Morris and Dodds, "Isolation and analysis of double-stranded RNA from virus-infected plant and fungal tissue", Phytopathology, 69:854-858 (1979).
Rogers et al., "A mitochondrial target for double-stranded RNA in diseased isolates of the fungus that causes Dutch elm disease", Nature 329:558-560 (1987).
Hammar et al., "Association of double-stranded RNA with low virulence in an isolate of Leucostoma persoonii", Phytopthology 79:568-572 (1989).
Bottacin et al., "Characterization of dsRNA in Chalara elegans and effects on growth an virulence", Phytopathology 84:303-312 (1994).
Bandy and Tavantzis, "Effect of hypovirulent Rhizoctonia solani on Rhizoctonia disease, growth, and development of potato plants", American Potato J. 67:189-199 (1990).
Chen et al., "Mitotic stability and nuclear inheritance of integrated viral cDNA in engineered hypovirulent strains of the chestnut blight fungus", EMBO J. 12:2991-2998 (1993).
Grente and Berthelay-Sauret, "Biological control of chestnut blight in France", Proceedings of the American Chestnut Symposium, pp. 30-34, eds. MacDonald et al., University of W. Virgina Press, Morgantown (1978).
Jaynes and Elliston, "Control of Endothia parasitica cankers on American chestnut sprouts with hypovirulent strains", Proceedings of the American Chestnut Symposium, pp. 110-114, eds. MacDonald et al., University of W. Virginia Press, Morgantown (1978).
Chen et al., "Attenuation of fungal virulence by synthetic infectious hypovirus transcripts", Science 264:1762-1764 (194).
Craven et al., "Papain-like protease p29 as a symptom determinant encoded by a hypovirulence-associated virus of the chestnut blight fungus", J. of Virology 67:6513-6521 (1993).
Chen et al., "cDNA-derived hypovirus RNA in transformed chestnut blight fungus is spliced and trimmed of vector nucleotides", Virology 202:441-448 (1994).
Websters Ninth New Collegiate Dictionary (1990) p. 1253.

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