Attenuation of ethyl alcohol intoxication with alpha-2 adrenocep

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514397, 514811, A61K 31415

Patent

active

049686925

ABSTRACT:
A method is provided for attenuating the intoxicating effects of ethyl alcohol in a patient, by administering to a patient in need thereof, an alpha-2 adrenoceptor antagonist compound. Two preferred compounds useful in the present invention, each being a highly potent and selective alpha-2 adrenoceptor antagonist, are atipamezole and idazoxan.

REFERENCES:
patent: 4640924 (1987-02-01), White et al.
patent: 4673680 (1987-06-01), Pendleton
patent: 4686226 (1987-08-01), Huff et al.
patent: 4690928 (1987-09-01), Huff et al.
patent: 4788202 (1988-11-01), Ward

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