Attenuated pseudorabies virus which has a deletion in at least a

Details Attenuated pseudorabies virus which has a deletion in at least a Attenuated pseudorabies virus which has a deletion in at least a

1985-09-06

1989-10-31

Warden, Robert J.

Chemistry: molecular biology and microbiology

Virus or bacteriophage, except for viral vector or...

4351721, 4351723, 435236, 435238, 435948, 424 89, 935 29, 935 56, 935 57, 935 65, C12N 700

Patent

active

048777374

ABSTRACT:
Attenuated pseudorabies viruses are provided which comprise DNA including a sequence essential for replication of the attenuated virus, at least a portion of which is present in a sequence essential for replication of a naturally-occurring pseudorabies virus, from which at least a portion of a repeat sequence has been deleted. These viruses are useful as vaccines for immunizing animals against pseudorabies virus disease.
The invention also provides methods of preparing attenuated pseudorabies viruses.

REFERENCES:
patent: 4514497 (1985-04-01), Kit et al.
patent: 4680176 (1987-07-01), Berns et al.
Post et al., PNAS, 77:4201-4205 (1980).
Koomey et al., J. Virol., 50:662-665 (1984).
Tenser et al., J. Clin. Microb., 17:122-127 (1983).
Price et al., Infection and Immunity, 34:571-580 (1981).
Thompson et al., Virology, 131:180-192 (1983).
Tenser et al., J. Gen. Virol., 64:1369-1373 (1983).
Gielkens et al., J. Gen. Virol., 66:69-82 (1985).
Lomniczi et al., J. Virol., 49:970-979 (1984).
Ben-Porat et al., Ninth International Herpesvirus Workshop, Seattle, Aug. 19-24, 1984.
L. E. Post et al., Cell 24, 555-565, 1981.
S. Kit et al., Herpesvirus Meeting, ICN-UCLA Symposium Abstract, Apr. 8-13, 1984.
S. Kit et al., Ninth International Herpesvirus Workshop, Seattle, Aug. 24-29, 1984.
B. Roizman et al., Cold Spring Harbor Conference on New Approaches to Viral Vaccines, Sep. 1983.
A. Tanaka et al., Herpesvirus Meeting, Keystone Company, 1984.

Affiliated with

Also associated with

Rating

Attenuated pseudorabies virus which has a deletion in at least a does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Attenuated pseudorabies virus which has a deletion in at least a, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Attenuated pseudorabies virus which has a deletion in at least a will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-625663