Attenuated polioviruses

Chemistry: molecular biology and microbiology – Virus or bacteriophage – except for viral vector or... – Inactivation or attenuation; producing viral subunits

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4351723, 424 93A, C12N 704, C12N 1509, C12N 701, A61K 3913

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052984133

ABSTRACT:
An attenuated enterovirus or rhinovirus, suitable for use as a vaccine, has an attenuating mutation at least at a position which is, or corresponds with, position 471 or 484 of the genome of poliovirus type 3 Leon strain.

REFERENCES:
Kuge et al. (May 1987), J. Virol. vol. 61(5), pp. 1478-1487.
Pilipenko et al. (1989), Virology 168: 201-209.
Nomoto et al. (1982), Proc. Natl. Acad. Sci USA 79:5793-5797.
Rivera et al. (1988), Virology 165: 42-50.
La Monica et al. (1986), J. Virol. 57(2): 515-525.
Suitkin et al. (1988), Virology 166: 394-404.
Skinner et al. (1989), J. Mol. Biol. 207: 379-392.
Stanway et al. (1986), J. Virol. 57(3): 1187-1190.
Cann et al. (1984), Nucl. Acids Res. 12(20): 7787-7792.
Stanway et al. (1983), Nucl. Acids Res. 11(16): 5629-5643.
Nomoto et al. (1987), UCLA Symp. Mol. Cell. Biol. (New Series) 54:437-452.
Ren et al. (1991), J. Virol. 65(3): 1377-1382.
Almond et al. (1988), Chem. Abstracts 109, Abstract No. 228104S.
Blinov et al. (1988), Chem. Abstracts 108, Abstract No. 144367W.
P. D. Minor et al. "The effect of sequences in the 5'. . . " J. Gen. Virol. (1988) 69, pp. 1091-1096.
A. Z. Zelent et al. "Replicative Intermediate of . . . " J. Virol., 1987), (Sep. 1987), pp. 2921-2923.
A. J. Macadam et al. "The 5' noncoding region of the type . . . " Virology, 181(1991) pp. 451-458.
R. Ruibao et al. "Indentification of two determinants . . . " Chemical Abstracts #118401g, vol. 114 No. 13 (1991), p. 414.
Minor et al. "The effect of sequences . . . " J. Gen. Virol. (1988), 69, pp. 1091-1096.
Pelletier, et al. "Mutational Analysis of Upstream . . . " Jour. of Virol., Dec. 1988m vol. 62 No. 12, pp. 4486-4492.
Stanway, et al. "Comparison of the complete nucleotide . . . " Proc. Natl Acad. of Science, vol. 81 Mar. 1984, pp. 1539-1543.
Toyoda et al. "Complete nucleotide sequences . . . " J. Molecular Biol. 1984 vol. 124, pp. 263-270.
Biological Abstracts vol. 84 No. 107609.
Evans et al. "Increased neuvirulence . . . " Nature, vol. 314 Apr. 11, 1985, pp. 548-550.
Van Der Weft et al. "Synthesis of . . . " Proc. Natl Acad Sci vol. 83 Apr. 1986 pp. 2330-2334.
Almond et al. J. Virol. Meth, vol. 17 (1-2) (1987).
La Monica et al. J. Virol. vol. 61(9) (1987) pp. 2917-2920.
Gillis Dewalt et al. J. Virol. vol. 61(7) (1987) pp. 2162-2170.

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