Attenuated mycobacteria as vectors for gene delivery to...

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...

Reexamination Certificate

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Details

C536S023100, C536S023700, C424S093100, C424S093200, C424S093210, C424S184100, C424S200100, C424S234100

Reexamination Certificate

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07939089

ABSTRACT:
Provided are mycobacteria comprising a recombinant gene operably liked to a mammalian promoter that directs expression of the recombinant gene from a mammalian cell. Also provided are mammalian cells comprising the above mycobacteria. Additionally provided are mycobacterial plasmids capable of replication in a mycobacterium. Further provided are methods of expressing a recombinant gene in a mammalian cell.

REFERENCES:
patent: 5783386 (1998-07-01), Jacobs, Jr. et al.
patent: 5877159 (1999-03-01), Powell et al.

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