Attenuated flavivirus strains containing a mutated...

Details Attenuated flavivirus strains containing a mutated... Attenuated flavivirus strains containing a mutated...

2007-03-13

2007-03-13

Campell, Bruce R. (Department: 1648)

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Virus or component thereof

C424S192100, C424S196110, C435S005000

Reexamination Certificate

active

10608029

ABSTRACT:
The present invention relates to nine residue peptides (ApoptoM) from flavivirus M ectodomain able to modulate specifically the apoptotic activity of diverse flavivirus, to pharmaceutical composition comprising the same and their use for the treatment and/or the prevention of flavivirus-linked infections and cancers.

REFERENCES:
patent: 6180604 (2001-01-01), Fraser et al.
Chang et al. “Recent advancement in flavivirus vaccine development,” Expert Rev. Vaccines 3(2), 199-220 (2004).
Meeting report: Review on Flavivirus Vaccine Development; Proceedings of a meeting jointly organised by the World Health Organization and the Thai Ministry of Public Health, Apr. 26-27, 2004, Bangkok, Thailand. Vaccine 23 (2005) 2689-2695.
U.S. Appl. No. 10/608,029, filed Jun. 30, 2003, Despres, et al.
U.S. Appl. No. 10/608,147, filed Jun. 30, 2003, Despres, et al.

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