Chemistry: molecular biology and microbiology – Virus or bacteriophage – except for viral vector or... – Inactivation or attenuation; producing viral subunits
Patent
1994-11-08
1998-09-29
Achutamurthy, Ponnathapura
Chemistry: molecular biology and microbiology
Virus or bacteriophage, except for viral vector or...
Inactivation or attenuation; producing viral subunits
4352351, 4241861, 4242041, 536 2372, 536 241, C12N 704, C12N 700, A61K 3912, C07H 2104
Patent
active
058145109
ABSTRACT:
The invention is directed to a novel attenuated canine parvovirus (CPV) strain which may be used as a veterinary vaccine against CPV disease. The invention is further directed to a virus stock generated from a genomic DNA clone of the attenuated CPV strain which is used as a veterinary vaccine and is able to confer protective immunity to dogs against challenge with virulent CPV. Methods are given for the production of an attenuated CPV virus from a cloned CPV genome which may be used as a veterinary vaccine.
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Carmichael Leland E.
Gruenberg Allen
Parrish Colin R.
Achutamurthy Ponnathapura
Cornell Research Foundation Inc.
Park Hankyel T.
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