Attachment of unmodified nucleic acids to silanized solid phase

Details Attachment of unmodified nucleic acids to silanized solid phase Attachment of unmodified nucleic acids to silanized solid phase

1997-06-06

1999-07-06

Sisson, Bradley L.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

435 911, 4352872, 436 94, 536 231, 536 243, 536 253, C12Q 168, G01N 3300, C12M 100, C07H 2102

Patent

active

059196262

ABSTRACT:
The invention relates to a simple, cost effective method for immobilizing synthetic nucleic acid molecules onto a solid support. The invention further concerns the use of such immobilized molecules in nucleic acid hybridization assays, sequencing by hybridization assays, and genetic analyses and combinatorial analyses involving nucleic acids or proteins for screening applications.

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