Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Patent
1998-09-17
1999-11-23
Achutamurthy, Ponnathapura
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
435183, 4352523, 435325, 4353201, 536 231, 536 232, 536 235, C12Q 168, C12N 900, C12N 1500, C07H 2104
Patent
active
059898224
ABSTRACT:
The invention provides a human ATP synthase subunit homolog (ASYNT) and polynucleotides which identify and encode ASYNT. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating or preventing disorders associated with expression of ASYNT.
REFERENCES:
Belogrudov, G.I. et al., "Membrane Topography and Near-neighbor Relationships of the Mitochondrial ATP Synthase Subunits e, f, and g", J. Biol. Chem. 271(34): 20340-20345 (1996).
Hartzog, P.E. and Cain, B.D., "The a.sub.leu207->arg Mutation in F.sub.1 F.sub.0 -ATP Synthase from Escherichia coli", J. Biol. Chem. 268(17): 12250-12252 (1993).
Sutliff, T.D. et al., (Direct submission), GenBank Sequence Database (Accession 100657), National Center for Biotechnology Information, National Library of Medicine, Bethesda, Maryland, 20894 (GI 100657), Dec. 6, 1996.
Baughn Mariah R.
Corley Neil C.
Guegler Karl J.
Tang Y. Tom
Achutamurthy Ponnathapura
Incyte Pharmaceuticals Inc.
Muenzen Colette C.
Slobodyansky Elizabeth
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