ATP synthase subunit homolog

Drug – bio-affecting and body treating compositions – Enzyme or coenzyme containing – Hydrolases

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435195, A61K 3846

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active

06036954&

ABSTRACT:
The invention provides a human ATP synthase subunit homolog (ASYNT) and polynucleotides which identify and encode ASYNT. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating or preventing disorders associated with expression of ASYNT.

REFERENCES:
Belogrudov, G.I. et al., "Membrane Topography and Near-neighbor Relationships of the Mitochondrial ATP Synthase Subunits e, f, and g", J. Biol. Chem. 271(34): 20340-20345 (1996).
Hartzog, P.E. and Cain, B.D., "The a.sub.leu207->arg Mutation in F.sub.1 F.sub.0 -ATP Synthase from Escherichia coli", J. Biol. Chem. 268(17): 12250-12252 (1993).
Sutliff, T.D. et al., (Direct Submission), GenBank Sequence Database (Accession 100657), National Center for Biotechnology Information, National Library of Medicine, Bethesda, Maryland, 20894 (GI 100657), Dec. 6, 1996.

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