Atmospheric pressure ion source probe for a mass spectrometer

Radiant energy – Ionic separation or analysis – With sample supply means

Reexamination Certificate

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C250S281000, C250S282000

Reexamination Certificate

active

07977629

ABSTRACT:
An ion source able to ionize both liquid and gaseous vapors from interfaced liquid separation techniques and a solids/liquid atmospheric pressure (AP) probe. The liquid effluents are ionized by electrospray ionization, photoionization or atmospheric pressure chemical ionization and the vapors released from a probe device placed in a heated gas stream in the AP source are ionized by a corona or Townsend electrical discharge or photoionization. The source has the ability to ionize compounds from both liquid and solid sources, which facilitates ionization of volatile and semivolatile compounds by applying heat from a gas stream as well as highly non-volatile compounds infused by electrospray or separated by liquid chromatography or capillary electrophoresis.

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patent: 7544933 (2009-06-01), Cooks et al.
patent: 2004/0094706 (2004-05-01), Covey et al.
patent: 2006/0125477 (2006-06-01), Killoran et al.
patent: 2006/0145089 (2006-07-01), Cristoni et al.
patent: 2008/0272286 (2008-11-01), Vestal
patent: 2010/0096542 (2010-04-01), Whitehouse et al.

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