Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving transferase
Reexamination Certificate
2007-01-09
2007-01-09
Prouty, Rebecca E. (Department: 1652)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving transferase
C435S007400, C435S007920, C435S194000, C514S350000, C514S012200
Reexamination Certificate
active
11076405
ABSTRACT:
The present invention provides methods for detecting activation of ATM kinase, DNA damage, and DNA damaging agents. Further provided are antibodies which specifically recognize the phosphorylation state of Ataxia Telangiectasia-Mutated (ATM) kinase. Methods of identifying agents which modulate the activation and activity of ATM kinase are also provided.
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Bakkenist Christopher
Kastan Michael B.
Darby & Darby
Gebreyesus Kagnew
Prouty Rebecca E.
St. Jude Children's Research Hospital
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