Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Reexamination Certificate
2005-07-12
2005-07-12
Prouty, Rebecca (Department: 1652)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
C435S007200, C435S015000, C435S007920, C435S194000, C514S012200, C514S350000
Reexamination Certificate
active
06916627
ABSTRACT:
The present invention provides methods for detecting activation of ATM kinase, DNA damage, and DNA damaging agents. Further provided are antibodies which specifically recognize the phosphorylation state of Ataxia Telangiectasia-Mutated (ATM) kinase. Methods of identifying agents which modulate the activation and activity of ATM kinase are also provided.
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Bakkenist Christopher
Kastan Michael B.
Gebreyesus Kagnew
Prouty Rebecca
St. Jude Children's Research Hospital
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