Atherosclerotic plaque specific antigens, antibodies thereto, an

Details Atherosclerotic plaque specific antigens, antibodies thereto, an Atherosclerotic plaque specific antigens, antibodies thereto, an

1993-04-26

1999-09-21

Scheiner, Toni R.

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

Blood proteins or globulins, e.g., proteoglycans, platelet...

5303911, 5303913, 436543, 435 11, 522544, C07K 1618, C12P 2108

Patent

active

059555840

ABSTRACT:
The subject invention provides a naturally occurring antigen indicative of the presence of atherosclerotic plaque. The subject invention provides a murine-human chimeric monoclonal antibody which specifically binds to an antigen indicative of the presence of atherosclerotic plaque; and methods and reagents involving the use of the murine-human chimeric monoclonal antibody. The subject invention provides a CDR-grafted antibody; and methods and reagents involving the use of the CDR-grafted antibody. The subject invention provides a surrogate antigen; methods and reagents involving the use of the surrogate antigen, preparation of the surrogate antigen, antibodies generated from the surrogate antigen.

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