ATCC HB8209, its monoclonal antibody to erythropoietin and assay

Details ATCC HB8209, its monoclonal antibody to erythropoietin and assay ATCC HB8209, its monoclonal antibody to erythropoietin and assay

1988-06-30

1992-04-21

Rosen, Sam

Chemistry: analytical and immunological testing

Involving an insoluble carrier for immobilizing immunochemicals

436532, 436536, 436547, 436548, 436817, 435 71, 435 7021, 4351722, 530326, 530329, 530806, 5303879, 53038823, 935102, 935110, G01N 3353

Patent

active

051067609

ABSTRACT:
Disclosed is a new mouse-mouse hybridoma tumor cell line A.T.C.C. No. HB8209. A monoclonal antibody produced by said cell line is specifically immunologically reactive with erythropoietin and with a polypeptide whose amino acid sequence is substantially duplicative of a sequence extent in erythropoietin. Disclosed also are procedures for isolation of erythropoietin by affinity purification and for quantitative detection of erythropoietin in fluid samples.

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