Asymmetric synthesis of R and S warfarin and its analogs

Details Asymmetric synthesis of R and S warfarin and its analogs Asymmetric synthesis of R and S warfarin and its analogs

1996-07-11

1997-11-11

Owens, Amelia

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D31102

Patent

active

056866313

ABSTRACT:
The present invention provides a novel process for making compounds of formula 2a or 2b or pharmaceutically acceptable salts thereof, ##STR1## wherein R1 is selected from the group consisting of phenyl and phenyl substituted with at least one group selected from NO.sub.2 and halogen;

REFERENCES:
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Armstrong et al., Anal. Chem. 66, 4278-4282 (1994).
Soini et al., Anal. Chem. 66, 3477-3484 (1994).
Bargmann-Leyder et al., Chromatographia 37(7/8), 433-443 (1993).

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