Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Patent
1996-11-22
1999-01-05
Rotman, Alan L.
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
564336, C07D21302, C07C21101
Patent
active
058564977
ABSTRACT:
This invention relates to process for asymmetrically producing enantiomerically pure .alpha.-cycloalkylalkyl substitututed methanamines from .alpha.-pinene. One key step of the process of this invention utilizes the oxidation product of .alpha.-pinene, hydroxy pinanone, as a chiral auxiliary to direct the stereoselective alkylation of the corresponding ketimine. This invention also relates to key intermediates useful in the processes referred to herein.
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Landi John
Roth Gregory
Aulakh Charanjits S.
Boehringer Ingelheim Pharmaceuticals Inc.
Devlin Mary-Ellen
Raymond Robert P.
Rotman Alan L.
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