Organic compounds -- part of the class 532-570 series – Organic compounds – Amino nitrogen containing
Patent
1996-07-15
1997-12-16
Shah, Mukund J.
Organic compounds -- part of the class 532-570 series
Organic compounds
Amino nitrogen containing
564184, 564218, 564391, C07C21100, C07C 5116
Patent
active
056987412
ABSTRACT:
An improved synthesis of a highly potent HIV reverse transcription inhibitor is disclosed, involving an acetylide and a trifluoromethyl ketone which produces a chiral product in the presence of a chiral amino alcohol.
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Corley Edward G.
Grabowski Edward J. J.
Thompson Andrew S.
Yasuda Nobuyoshi
Camara Valerie J.
Daniel Mark R.
Merck & Co. , Inc.
Ngo Tamthom T.
Shah Mukund J.
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