Asymmetric synthesis of 3-substituted furanoside compounds

Details Asymmetric synthesis of 3-substituted furanoside compounds Asymmetric synthesis of 3-substituted furanoside compounds

1991-05-10

1993-06-01

Griffin, Ronald W.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536 182, 536 172, 536 175, 536 184, 536 187, 536 54, 536 553, 536 63, 536 181, 536 174, 536124, C08B 3700, C07H 100, C07H 300, C07H 1500

Patent

active

052161455

ABSTRACT:
Novel processes, intermediates and reagents for the preparation of 3-substituted furanose or furanoside compounds of Formula I: ##STR1## wherein M is hydrogen or alkyl (C.sub.1 -C.sub.3), A is halogen or A may be selected from a moiety of the formula: OR, SR, N.sub.3, SCR, OC-R or CN wherein R is hydrogen, branched or unbranched alkyl (C.sub.1 -C.sub.4) or phenyl which compounds have antiviral and other biological activity.

REFERENCES:
Fleet, G. W. et al., Tetrahedron, 1988, 44(2): 625-636.
Bravo, P. et al., J. Org. Chem., 1989, 54: 5171-5176.
Y. Gao et al., J. Amer. Chem. Soc., 1987, 109: 5765-5780.

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