Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2005-04-01
2009-08-18
McKane, Joseph K. (Department: 1626)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C548S439000
Reexamination Certificate
active
07576118
ABSTRACT:
The present invention provides an asymmetric hydrogenation process for the preparation of chiral cycloalkanoindole DP receptor antagonists in high enantiomeric excess.
REFERENCES:
patent: 4962230 (1990-10-01), Takaya et al.
patent: WO 03/062200 (2003-07-01), None
patent: WO 2005/013985 (2005-02-01), None
R. Noyori, et al.,J. Am. Chem. Soc.,108, pp. 7117-7119, (1986)—XP-002337343.
Humphrey Guy R.
Tellers David M.
Brown Dianne
Coppins Janet L
Daniel Mark R.
McKane Joseph K.
Merck & Co. , Inc.
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