Asymmetric cyanine fluorescent dyes

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C546S166000, C548S121000, C436S089000, C436S090000, C436S092000, C436S096000, C436S800000

Reexamination Certificate

active

07598385

ABSTRACT:
The present disclosure provides the asymmetric cyanine fluorescent dyes of formula I in which X, n, R1, R2, R3, R4, R5and Y−are as defined in the specification. The present disclosure also provides conjugates of the fluorescent dyes, methods for preparation thereof, compositions comprising the fluorescent dyes, and methods for staining biological samples using the fluorescent dyes and compositions thereof.

REFERENCES:
patent: 4414325 (1983-11-01), Masuda et al.
patent: 4957870 (1990-09-01), Lee et al.
patent: 5958776 (1999-09-01), Sakata et al.
patent: 5994138 (1999-11-01), Veriac
patent: 6004816 (1999-12-01), Mizukami et al.
patent: 6245499 (2001-06-01), Suzuki et al.
patent: 2003/0145394 (2003-08-01), Wang et al.
patent: 1183559 (1998-06-01), None
patent: 1149397 (2004-05-01), None
U.S. Appl. No. 12/334,274, Shao.
Jason A. Bordelon et al., “Viscometry and Atomic Force Microscopy Studies of the Interactions of a Dimeric Cyanine Dye with DNA,” J. Phys. Chem. B 2002, 106, 4838-4843.
Alexandre Furstenberg et al., “Ultrafast Excited-State Dynamics of DNA Fluorescent lntercalators: New Insight Into the Fluorescence Enhancement Mechanism,” J. Am. Chem. Soc. 2006, 128, 7661-7669.
Kristine M. Sovenyhazy et al., “Spectroscopic studies of the multiple binding modes of a trimethine-bridged cyanine dye with DNA,” Nucleic Acids Research, vol. 31 No. 10, 2561-2569.
L. G. S. Brooker et al., “Absorption of Unsymmetrical Carbocyanines,” J. Amer. Chem. Soc., 1945, 67, 1889-93.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Asymmetric cyanine fluorescent dyes does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Asymmetric cyanine fluorescent dyes, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Asymmetric cyanine fluorescent dyes will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-4109523

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.