Asymmetric conjugate addition reaction using a chiral additive

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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546339, 546340, 546341, C07D21170, C07D21172

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active

059986255

ABSTRACT:
This invention relates to a process for the preparation of a key intermediate using an chiral additive to effect an asymmetric conjugate addition.

REFERENCES:
patent: 5389620 (1995-02-01), Ishikawa et al.
patent: 5714479 (1998-02-01), Ishikawa et al.
Chemical Abstracts 124:175888, abstract of Leonard, Tetrahedron (1995), 51(47), pp. 12843-12858.
chemical Abstracts 122:81251, abstract of Castle, Tetrahedron Lett, (1994), 35(40), pp. 7455-7458.
Chemical Abstracts 117:47646, abstract of Christenson, Tetrahedron, (1992), 48(17), pp. 3623-3632.

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