Asymmetric catalysis

Details Asymmetric catalysis Asymmetric catalysis

1977-08-17

1980-03-18

Killos, Paul J.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acid esters

560152, 560170, 560185, 562470, 562579, C07C 6976

Patent

active

041940512

ABSTRACT:
Catalytic asymmetric hydrogenation of a compound of the formula ##STR1## wherein R, R.sup.1 and R.sup.2 each independently represent hydrogen, substituted or unsubstituted alkyl having from 1 to 5 carbon atoms or substituted or unsubstituted aryl, and R.sup.3 represents substituted or unsubstituted alkyl having from 1 to 5 carbon atoms or substituted or unsubstituted aryl, provided that, if only one of R and R.sup.1 is hydrogen the Z geometric isomer is hydrogenated, in the presence of a homogeneous, coordination complex catalyst comprising rhodium, iridium or ruthenium in combination with an optically active bis phosphine ligand provides an excellent level of optical purity.

REFERENCES:
House, H. O., Modern Synthetic Reactions, pp. 28-34, 1972.

Affiliated with

Also associated with

Rating

Asymmetric catalysis does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Asymmetric catalysis, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Asymmetric catalysis will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1124725