Astrocyte apparatus for bioprocessing a circulating fluid

Chemistry: molecular biology and microbiology – Apparatus – Bioreactor

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C12M 112

Patent

active

061365939

ABSTRACT:
The invention relates to a container having astrocytes for use in removing toxins from a biological fluid. The container includes a first port for receiving the biological fluid and a second port through which the biological fluid exits the container. The invention also relates to a method of treating a biological fluid by contacting it with astrocytes.

REFERENCES:
patent: 5643794 (1997-07-01), Liu et al.
Booher, J. et al., "Growth and Cultivation of Dissociated Neurons and Glial Cells from Embryonic Chick, Rat and Human Brain in Flask Cultures," Neurobiology, vol. 2, pp. 97-105, 1972.
Butterworth, Roger F., "Portal-Systemic Encephalopathy: A Disorder of Neuron-Astrocytic Metabolic Trafficking," Dev Neurosci, vol. 15, pp. 313-319, 1993.
Norenberg, Michael D. et al., "Fine Structural Localization of Glutamine Synthetase in Astrocytes of Rat Brain," Brain Research, vol. 161, pp. 303-310, 1979.

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