Astaxanthin-producing yeast cells, methods for their preparation

Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Hydrolase

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435 67, C12N 116, C12P 2300

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053568109

ABSTRACT:
An isolated pure culture of a strain of Phaffia rhodozyma which produces astaxanthin in an amount of at least 600 .mu.g per g Phaffla rhodozyma dry matter, as determined by HPLC analysis.

REFERENCES:
patent: 5182208 (1993-01-01), Johnson et al.
Stewart, G. G., "The Genetic Manipulation of Industrial Yeast Strains", Can. J. Microbiol. vol. 27, pp. 973-990, 1981.
Tubb, R. S., "Genetic Development of Yeast Strains", Brewers' Guardian, pp. 34-37, 1984.
Jacobson, G. K., "Mutations", pp. 297-298, In Biotechnology vol. 1, 1981 Verlag Chemie.
Okagbue et al., Appl. Microbiol Biotechnol., vol. 20, pp. 33-39, 1984.
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Merck Index, Tenth Edition, p. 174, 1983.
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Norsk Fiskeoppdrett nr. 3-85, pp. 4-6, Berit Kvalheim og Gjert Knutsen, "Pigmentering av laks med astaxanthin fra mikroalger" (& English trans.) 1983.
Biotechnology Letters vol. 6, No. 4, 1984, pp. 247-250, Okagbue R. N. et al., "Autolysis of the Red Yeast Phaffia rhodozyma: A Potential Tool to Facilitate Extraction of Astaxanthin".
J. Fish Board Can., vol. 34, 1977, pp. 2417-2421, Johnson, Eric A. et al, "The Yeast Phaffia rhodozyma as a Dietary Pigment Source for Salmonids adn Crustaceans".
Research Proposal entitled "Microbial Production of Astaxanthin For Salmonid and Lobster Pigmentation" submitted at Massachusetts Institute of Technology (MIT) in Oct. 1978.

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