Assessment of cervical cells

Details Assessment of cervical cells Assessment of cervical cells

2005-03-22

2005-03-22

Canella, Karen A. (Department: 1642)

Chemistry: analytical and immunological testing

Cancer

C530S388100, C530S388800

Reexamination Certificate

active

06869801

ABSTRACT:
A method of determining premalignant or neoplastic disease state in a tissue sample containing cells of the cervix, the method comprising contacting specific monoclonal antibodies to a cervical tissue sample, determining binding of the antibodies to the sample and comparing the binding with a pattern of binding of the same antibodies to a normal cervical cell sample. Hybridomas which produce suitable antibodies have been deposited at the European Collection of Animal Cell Cultures (ECACC) under the accession numbers ECACC 95020718, 95020716, 95020720, 95020717 and 95020719.

REFERENCES:
patent: 4666845 (1987-05-01), Mattes et al.
patent: 4714680 (1987-12-01), Civin
patent: 4965204 (1990-10-01), Civin
patent: 2 215 046 (1989-09-01), None
Eltabbakh et al., Obstetrics and Gynecology, 85(4):499-503, Apr. 1995.*
Kamiya et al., Acta Cytologica, 37(2):131-134, Apr. 1993.*
Smedts, et al., American Journal of Pathology, 142(2):403-412, Feb. 1993.*
Stedman's Medical Dictionary, p. 1456, 24 ed., Williams & Wilkens, Baltimore, 1982.*
The abstract of Buchler et al (Archives of Gynecology, 1983, vol. 233 pp. 121-130).*
Malecha et al (International Journal of Gynecological Pathology, 1992, vol. 11, pp. 24-29).*
Epenetos et al., “Targeting of iodine-123-labelled tumour-associated monoclonal antibodies to ovarian, breast and gastrointestinal tumours,” The Lancet, Nov. 6, 1982, 999-1004.
Epenetos, A.A., “Antibody guided lymphangiography in the staging of cervical cancer,” Br. J. of Cancer, 51: 805-808 (1985).
Jha et al., “Monoclonal antibodies for the histopathological diagnosis of cervical neoplasia,” British Journla of Obstetrics and Gynaecology, 91: 483-488 (1984).
Porta et al., “Diagnosis of cervical carcinoma using the monoclonal antibodies technique,” Patologia e Clinica Ostetrica e Ginecologia, 14: 348-355 (1986). (Translation).
Holmes et al., “Expression of a Monoclonal Antibody-Defined Liver-Associated Antigen in Normal Rat Hepatocytes and Hepatocellular Carcinoma Cells,”Int. J. Cancer29:559-565 (1982).
Holmes et al., “Application of a Monoclonal Antibody to Rat Hepatocytes in the Study of Rat Liver Carcinogenesis,” Publication of the Proceedings of the Th Meeting of the European Association for Cancer Research Budapest, Oct. 12-15, 1981, 471-481.
Holmes et al., “A Monoclonal Antibody Reactive with Human Hepatocytes,”Liver3:295-302 (1983).
Holmes et al., “Monoclonal Antibodies Reacting with Normal Rat Liver Cells as Probes in Hepatocarcinogenesis,” Cancer Research, 44, 1611-1627 (Apr. 1984).
Prosperi Porta et al., “Diagnosis of Carcinoma of the uterine Cervix with Monoclonal Antibodies Technique,” Pat. Clin. Ost. Gin., 14:348-355 (1986). (English Abstract).

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