Assessment of bone fragility and prediction of osteoporotic frac

Details Assessment of bone fragility and prediction of osteoporotic frac Assessment of bone fragility and prediction of osteoporotic frac

1995-05-16

1999-12-21

Housel, James C.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving antigen-antibody binding, specific binding protein...

5303871, 5303882, 5303891, 5303898, 5303911, 5303913, 435 793, 435 794, 435 7021, 435810, 435975, 436 58, 436808, 436811, C07K 1600, G01N 3353, G01N 33543

Patent

active

060047658

ABSTRACT:
A method for the assessment of bone fragility and osteoporosis fracture risk characterized by:

REFERENCES:
patent: 4438208 (1984-03-01), Deftos et al.
Power, M. J. Osteocalcin: Diagnostic Methods and Clinical Applications. Critical Reviews in Clinical Lab Sciences. vol. 28 (4) (1991):pp. 287-235.
John Kanis et al., "The Diagnosis of Osteoporosis", Journal of Bone and Mineral Research, 9:1137-1141 (1994) (no month cited on the reference).
Journal of Biological Chemistry; vol. 255 No. 18; Sep. 25, pp. 8685-8691, 1980; "Isolation and Sequence of the Vitamin K-dependent Protein from Human Bone".
Journal of Bone and Mineral Research, vol. 6, No. 11, 1991 "Impairment of Gamma Carboxylation of Circulating Osteocalcin (Bone Gla Protein) in Elderly Women"; Plantlech et al.
Menon et al., "Impaired Carboxylation of Osteocalcin in Warfarin-Treated Patients", J. Clin. Endocrin. Metab., vol. 64, No. 1, (1987), pp. 59-61.
Hodges et al., "Depressed Levels of Circulating Menaquinones in Patients w/osteoporotic Fractures of The Spine and Femoral Neck," Bone, vol. 12, (1991), pp. 387-389.
Szulc et al., "Serum Undercarboxycated Osteocalcin is a Marker of the Risk of Hip Fracture in Elderly Women," J. Clin. Investg., vol. 91, (1993), pp. 1769-1774.

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