Surgery – Diagnostic testing – Cardiovascular
Patent
1997-11-03
2000-07-18
O'Connor, Cary
Surgery
Diagnostic testing
Cardiovascular
600481, A61N 500
Patent
active
060900474
ABSTRACT:
A novel method for estimating the end-systolic pressure-volume relationship (ESPVR) is presented. The method provides for accurate estimation of the ESPVR from a single beat of the cardiac cycle. The method is based on normalized human time varying elastance curves [E.sub.N (t.sub.N)]. The ESPVR is estimated from one beat using PV data measured at normalized time t.sub.N and end-systole (t.sub.max) to predict intercept: ##EQU1## and slope: E.sub.max(SB) =P(t.sub.max)/[V(t.sub.max)-V.sub.0(SB) ]. The present invention provides a method for ESPVR estimation which is non-invasive and particularly applicable for bedside applications.
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Chen Chen-Huan
Kass David A.
Senzaki Hideaki
Astorino Michael
Johns Hopkins University School of Medicine
O'Connor Cary
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