Optics: measuring and testing – Sample – specimen – or standard holder or support
Patent
1992-02-20
1993-05-04
McGraw, Vincent P.
Optics: measuring and testing
Sample, specimen, or standard holder or support
2504612, 356318, G01N 2101, G01N 2164
Patent
active
052086496
ABSTRACT:
A coverslip holder assembly for a front face fluorimetry flow cell has a holder body and a hingedly attached clamp for releasably maintaining a coverslip adjacent the front face of the holder body and flow cell. The assembly is preferably a unitary arrangement wherein the clamp is hingedly mounted adjacent the bottom end of the front face of the holder body, and has a convenient snap lock release mechanism at its top end to selectively lock the coverslip in flush arrangement with the front face. The holder assembly can provide a biased snug fit with a variety of cuvettes or similar sample vessels, and enables the use of highly colored or fluorescent compounds for perfusion in front face fluorimetry operations.
REFERENCES:
patent: 4008397 (1977-02-01), Zdrodowski
patent: 4279509 (1981-07-01), Daffern
patent: 4531834 (1985-07-01), Nogami
patent: 4989974 (1991-02-01), Anton et al.
patent: 5074662 (1991-12-01), Sullivan
Biomedical Article from Jan. 10, 1989, entitled "Measurement of Calcium in a Cultured Monolayer of Heartcells".
Article entitled "Fluorescence probe measurement of the intralysosomal pH in living cells and the perturbation of pH by various agents" Proc. Natl. Acad. Sci. USA, vol. 75 #7 pp. 3327-3331, Jul. 1978, Cell Biology.
Cuppoletti John
Langdon Nick H.
McGraw Vincent P.
University of Cincinnati
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