Drug – bio-affecting and body treating compositions – Lymphokine
Patent
1990-10-25
1994-03-29
Wax, Robert A.
Drug, bio-affecting and body treating compositions
Lymphokine
424 88, 514 12, 530350, 530826, 536 2372, A61K 3915, C07K 1300, C12N 1546
Patent
active
052982440
ABSTRACT:
Assembled viral particles derived from rotavirus proteins are disclosed. The assembled particles include the inner capsid protein, VP6, in combination with either or both of the outer capsid proteins, VP4 and VP7. These assemblies can be used in vaccine compositions for the treatment and prevention of rotaviral disease.
REFERENCES:
patent: 5071651 (1991-12-01), Sabara et al.
Ijaz et al., J. Virol. (1990) Pre-publication copy.
Flores et al., J. Clin. Microbiol. (1989) 27:512-518.
Estes et al., Microbiol. Rev. (1989) 53:410-449.
Sabara et al., J. Virol. (1985) 53:58-66.
Potter et al., Nucl. Acid Res. (1987) 15(10):4361.
Mackow et al., Proc. Natl. Acad. Sci. USA (1988) 85:645-649.
Offit et al., J. Virol. (1986) 58:700-703.
Redmond et al., Mol. Immunol. (1990) 28(3):269-278.
Ready et al., Virology (1988) 167:269-273.
Estes et al., J. Virol. (1987) 61(5):1488-1494.
Estes et al., Nucl. Acids Res. (1984) 12(4):1875-1887.
Ready et al., Virology (1987) 157:189-198.
Sabara et al., J. Gen Virol. (1987) 68:123-133.
Taniguchi et al., J. Virol. (1989) 63(9):4101-4106.
Bass et al., "NS35 and not VP7 is the soluble rotavirus protein which binds to target cells"Journal of Virology (1990) 64(1):322-330.
Chen et al., "Specific interactions between rotavirus outer capsid proteins VP4 and VP7 determine expression of a cross-reactive, neutralizing VP-4-specific epitope" Journal of Virology (1992) 66(1):432-439.
Ijaz et al., "Heterotypic passive protection induced by synthetic peptides corresponding to VP7 and VP4 of bovine rotavirus" Journal of Virology (1991) 65(6):3106-3113.
Redmond et al., "Rotavirus vaccinology" Kurstak, E., ed., Control of Virus Diseases (1992) Marcel Dekker, Inc., New York, Chapter 16, pp. 387-404.
Redmond et al., "Assembly of recombinant rotavirus proteins into virus-like particles and assessment of vaccine potential" Vaccine (1992) 11(2):273-281.
Redmond et al., "Rotavirus particles function as immunological carriers for the delivery of peptides from infectious agents and endogenous proteins" Molecular Immunology (1991) 28(3):269-278.
Brussow et al.,, J. Virol. (1990) 64(8):3635-3642.
Biologizal Abstracts/RRM 41:19066.
Shendan, J. E. et al. "Prevention of Rotavirus-Induced Diarrhea in Neonatal Mice Born to Dams Immunized with Empty Capsids of Simian Rotavirus SA-11", J. Infect. Diseasses 149 (3) 434-438 (Mar. 1984).
Ijaz Mohammed K.
Parker Michael D.
Redmond Mark J.
Prouty Rebeeca
University of Saskatchewan
Wax Robert A.
LandOfFree
Assembled viral particles and their use in a vaccine to rotavira does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Assembled viral particles and their use in a vaccine to rotavira, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Assembled viral particles and their use in a vaccine to rotavira will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-789821