Assays for the determination of carcinogenicity

Details Assays for the determination of carcinogenicity Assays for the determination of carcinogenicity

1982-03-23

1985-07-30

Padgett, Benjamin R.

Chemistry: analytical and immunological testing

Biospecific ligand binding assay

436504, 436 63, 436 64, 436 94, 436804, 436808, 436813, 435 6, 435 29, 4351722, 435810, 935 6, C12N 1500, C12Q 168, G01N 3350

Patent

active

045322201

ABSTRACT:
There is provided an assay for the determination of the carcinogenicity of chemical and physical agents, by exposing a selected line of tumor virus transformed cells to the agent to be tested and determining whether such exposure induces endogenous viral DNA replication in such cells, which induction is indicative of the carcinogenicity of the tested agent by in situ hybridization. There is provided a kit for carrying out such assay.

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