Assays for TERT promoter modulatory agents using a...

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid

Reexamination Certificate

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C435S455000

Reexamination Certificate

active

11085872

ABSTRACT:
Methods and compositions for assaying an agent for TERT promoter modulatory activity are provided. In the subject methods, an agent is contacted with a cell comprising a mutant telomerase structural RNA component (TR) that results in a detectable phenotype in the presence of telomerase reverse transcriptase (TERT). Also provided are compositions, systems and kits thereof, as well as devices, that find use in practicing the subject methods. The subject invention finds use in assaying agents for TERT promoter modulatory activity, such as in a high throughput format.

REFERENCES:
patent: 5972605 (1999-10-01), Villeponteau et al.
patent: 6610839 (2003-08-01), Morin et al.
patent: 6664046 (2003-12-01), Chang et al.
patent: 2004/0072787 (2004-04-01), Morin et al.
patent: WO 02/16657 (2002-02-01), None
patent: WO 02/16658 (2002-02-01), None
patent: WO 02/070668 (2002-09-01), None
patent: WO 02/072787 (2002-09-01), None
patent: WO 02/090570 (2002-11-01), None
patent: WO 02/090571 (2002-11-01), None
patent: WO 02/101010 (2002-12-01), None
patent: WO 03/000916 (2003-01-01), None
patent: WO 03/016474 (2003-02-01), None
Ducrest et al. Oncogene. 2002; 21:541-552.
Kim et al. PNAS 2001; 98:7982-87.
Li et al. Canc. Res. 2004; 64:4833-40.
Wang et al. Oncogene. 2002; 21:3517-24.
Won et al. PNAS. 2004; 101:11328-33.
Feng et al. 1995; 269:1236-41.
Marusic et al. (Mol. Cell Biol., 1997, 17(1): 6394-6401.
Li et al. “Rapid Inhbition of Cancer Cell Growth Induced by Lentiviral Delivery and Expression of Mutant Template Telomerase RNA and Anti-Telomerase Short-Interfering RNA,” (2004) Cancer Research, 64:4833-4840.

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