Chemistry: analytical and immunological testing – Peptide – protein or amino acid – Amino acid or sequencing procedure
Patent
1992-10-14
1995-08-01
Alexander, Lyle A.
Chemistry: analytical and immunological testing
Peptide, protein or amino acid
Amino acid or sequencing procedure
436174, 436825, 436 86, 436120, 436 4, 436 18, G01N 2400, C12Q 100
Patent
active
054380170
ABSTRACT:
Improved methods for the GC/MS analysis of sulfhydryl amino acids and methylmalonic acids in samples of body fluids are provided. Additionally a method for combined assay of sulfhydryl amino acids particularly total homocysteine and combined creatine/creatinine levels in samples of body fluids provided. The information provided by the methods described is useful in the detection of the presence of cobalamin or folate deficiencies in individuals and in distinguishing between the two deficiencies.
REFERENCES:
patent: 4940658 (1990-07-01), Allen et al.
Information Disclosure Statement submitted in parent application Ser. No. 345,885 dated Nov. 29, 1990.
Declaration under 37 CFR .sctn.1.132 dated Nov. 27, 1990, including Exhibit A thereto.
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Allen Robert H.
Stabler Sally P.
Alexander Lyle A.
The University of Colorado Foundation Inc.
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