Assays for functional nuclear receptors

Details Assays for functional nuclear receptors Assays for functional nuclear receptors

1995-12-08

1998-06-23

Jones, W. Gary

Drug, bio-affecting and body treating compositions

Radionuclide or intended radionuclide containing; adjuvant...

Attached to antibody or antibody fragment or immunoglobulin;...

435 6, 435 912, 435 71, 435 79, 435 72, 536 231, 536 243, 536 2433, A61K 500

Patent

active

057701768

ABSTRACT:
Methods and test kits for detecting, or detecting and quantitating functional nuclear receptors in cell or tissue samples are disclosed. Such methods provide highly sensitive assays requiring small sample sizes and short turnaround times. The methods are useful in developing prognoses and/or treatment programs for cancer patients, especially in determining whether therapy to interfere with the receptor's activation of gene transcription, such as, endocrine therapy, would be helpful.

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