Assays for diagnosis of thrombophilic disease

Details Assays for diagnosis of thrombophilic disease Assays for diagnosis of thrombophilic disease

2007-08-07

2007-08-07

Le, Long V. (Department: 1641)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving antigen-antibody binding, specific binding protein...

C435S007920, C435S007940, C435S013000, C435S332000, C436S063000, C436S069000, C424S009340

Reexamination Certificate

active

11028339

ABSTRACT:
The present invention provides methods for diagnosing and/or monitoring thrombophilic disease in a patient that can result from the antiphospholipid antibody syndrome (aPL syndrome). The methods of the invention are premised on the inhibition of binding of an anticoagulant protein, annexin, preferably annexin-V, to phospholipids by antiphospholipid (aPL) antibodies in a patient blood sample.

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