Assays for antibody to hepatitis B core antigen

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

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424 858, 424 86, 4351722, 43524027, 435810, 435948, 435 68, 436518, 436820, G01N 5300, G01N 33543, C12P 2100, C12N 1500

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048186880

ABSTRACT:
A single-antibody inhibition assay for detecting antibody to HBcAg using a labeled monoclonal antibody. A competitive ELISA method of screening hybridoma supernatants for monoclonal antibodies to HBcAg. A method of producing high affinity monoclonal antibody to rHBcAg by immunizing a mouse with rHRcAg using a short immunization schedule. Monoclonal antibodies to immunodominant epitope of HBcAg.

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Chemical Abstract 103(19): 156873.
Siddle, N. Alternative Immunoassays, Chapter 3, pp. 13-36, (1985).
Tietz, Clinical Guide to Laboratory Tests, pp. 268-269, (1983).
Kohler and Milstein, Nature, vol. 256, pp. 495-497, Aug. 7, 1975.
Cianfriglia et al., Hybridoma, vol. 12(4), 451-457 (1983).
Tedder et al., Journal of Hygiene, Cambridge, vol. 90, 135-142, 1983.
Tedder et al., Proceedings International Hepatitis Workshop, 201-208, 1983.
Furuya et al., Japan J. Med. Sci. Biol., 37 151-159 (1984).
Waters et al., J. Med. Virology, 19:79-86 (1986).
Tedder et al., Journal of Medical Virology, 6:323-332 (1980).

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