Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Reexamination Certificate
2011-06-21
2011-06-21
Chunduru, Suryaprabha (Department: 1637)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
C536S023100
Reexamination Certificate
active
07964355
ABSTRACT:
The present invention relates to the methods for assaying an analyte comprising a nucleic acid analog binding substrate in a sample, comprising reacting a catalytic complex comprising a nucleic acid analog, a nucleic acid analog specific binding substrate and a light reactive dye with a light stimulus, and detecting the presence or absence or amount of a reaction product of the catalytic complex and light stimulus. The present invention also relates to a method of assaying a nucleic acid analyte in a sample using an analyte-specific reporter complex. The present invention also relates to a method of assaying an analyte in a sample using a reporter molecule.
REFERENCES:
patent: 5034506 (1991-07-01), Summerton et al.
patent: 5340716 (1994-08-01), Ullman et al.
patent: 5641625 (1997-06-01), Ecker et al.
patent: 5705333 (1998-01-01), Shah et al.
patent: 5714331 (1998-02-01), Buchardt et al.
patent: 5719262 (1998-02-01), Buchardt et al.
patent: 5736336 (1998-04-01), Buchardt et al.
patent: 5766855 (1998-06-01), Buchardt et al.
patent: 5773571 (1998-06-01), Nielsen et al.
patent: 5786461 (1998-07-01), Buchardt et al.
patent: 6107470 (2000-08-01), Nielsen et al.
patent: 6225052 (2001-05-01), Batz et al.
patent: 6228982 (2001-05-01), Norden et al.
patent: 6357163 (2002-03-01), Buchardt et al.
patent: 6403763 (2002-06-01), Loew
patent: 6414112 (2002-07-01), Buchardt et al.
patent: 6441130 (2002-08-01), Egholm et al.
patent: 6451968 (2002-09-01), Egholm et al.
patent: 2003/0157500 (2003-08-01), Lowe
patent: 2003/0162699 (2003-08-01), Lowe
patent: 2007/0231821 (2007-10-01), Bupp et al.
patent: WO2005017181 (2005-02-01), None
patent: WO 2007100711 (2007-09-01), None
Antony T., et al., “Molecular Beacons: Nucleic Acid Hybridization and Emerging Applications,”J Biom Struct.&Dyn.,19(3):497-504 (2001).
Armitage, B., “Cyanine-Dye-DNA Interactions: Intercalation, Groove Binding, and Aggregation,”Top Curr Chem,253:55-76 (2005).
Jimenez-Banzo, et al., “Time-Resolved Methods in Biophysics. 7. Photon Counting vs. Analog Time-Resolved Singlet Oxygen Phosphorescence Detection,”Photochem Photobiol Sci,7:1003-1010 (2008).
Baeumner, et al., “A Universal Nucleic Acid Sequence Biosensor with Nanomolar Detection Limits,”Anal. Chem.,76(4):888-894 (2004).
Barta, C., et al., “Dansyl-And Rhodamine-Based Fluorescent Sensors for Detecting Singlet Oxygen and Superoxide Production in Plants in Vivo,”Proceedings of the 7thHungarian Congress on Plant Physiology,46(3-4):149-150 (2002).
Bentin, T, et al., “Superior Duplex DNA Strand Invasion by Acridine Conjugated Peptide Nucleic Acids,”J. Am Chem Soc,125(21):6378-6379 (2003).
Berger, M., “High performance liquid chromatography-electrochemical assay for monitoring the formation of 8-oxo-7,8-dihydroadenine and its related 2'-deoxynucleoside.,”J. Liquid Chromatogr.,13, 929-932 (1990).
Biver T., et al., “Cyanine Dyes as Intercalating Agents: Kinetic and Thermodynamic Studies on the DNA/Cyan40 and DNA/Ccyan2 Systems,”Biophy J,89:374-383 (2005).
Cell Biology: A Laboratory Handbook, J.E. Celis ed., vol. 2, Academic Press (1998).
Chandler, D., et al., “Affinity Capture and Recovery of DNA at Femotomolar Concentrations with Peptide Nucleic Acid Probes,”Analytical Biochemistry,283:241-249 (2000).
Chibisov, A.K., et al., “Photoprocesses in Dimers of Thiacarbocyanines,”Phys Chem Chem Phys,1:1455-1460 (1999).
Demidov, V. , et al., “Kinetics and Mechanism of the DNA Double Helix Invasion by Pseudocomplementary Peptide Nucleic Acids,”Proc Natl Acad Sci ,99(9):5953-5958 (2002).
Demidov, V.V.,et al., “Duplex DNA capture,”Current. Issues in Mol. Bio.2(1):31-35 (2000).
Demidov, V., et al., “Kinetics and Mechanism of Polyamide (“Peptide”) Nucleic Acid Binding to Duplex DNA,”Proc. Natl. Acad. Sci. USA,92:2637-2641 (1995).
Dilek, I., et al., “Effect of PNA Backbone Modifications on Cyanine Dye Binding to PNA-DNA Duplexes Investigated by Optical Spectroscopy and Molecular Dynamics Simulations,”J Am Chem Soc,127: 3339-3345 (2005).
Dizdaroglu, M., “Chemical Determination of Free Radical-Induced Damage to DNA,”Free Rad Biol. Med.,10:225-242 (1991).
Egholm M., et al., “PNA Hybridizes to Complementary Oligonucleotides Obeying the Watson-Crick Hydrogen-Bonding Rules,”Nature,365:566-568 (1993).
Floyd, R.A., et al., “Hydroxyl Free Radical Adduct of Deoxyguanosine: Sensitive Detection and Mechanism of Formation,”Free Rad. Res. Commun.,1(3):163-172 (1986).
Freshney, R.I., Animal Cell Culture (1987).
Geiger, A., et al., “PNA Array Technology in Molecular Diagnostics,”Nucleosides&Nucleotides,17(9-11):1717-1724 (1998).
Glazer, A.N. et al., “Stable Dyne-DNA Intercalation Complexes as Reagents for High-Sensitivity Fluorescence Detection,”Nature,359:859-861 (1992).
Gomes A., et al., “Fluorescence probes Used for Detection of Reactive Oxygen Species,”J Biochem Biophys Methods,65:45-80 (2005).
Hannah K.C., et al., “1H NMR and Optical Spectroscopic Investigation of the Sequence-Dependent Dimerization of a Symmetrical Cyanine Dye in the DNA Minor Groove,”Biochemistry.44:15924-15929 (2005).
Hoebeke M., et al., “Singlet Oxygen Production of Photoisomerization: Two Competitive Processes for Merocyanine 540 Irradiated with Visible Light,” J.Photochem. Photobio., B. Biology,1:437-446 (1988).
Jensen, K., et al., “Kinetics for Hybridization of Peptide Nucleic Acids (PNA) with DNA and RNA Studies with the BIAcore Technique,”Biochemistry,36:5072-5077 (1997).
Kaihatsu, K., et al., “Enhanced Strand Invasion by Peptide Nucleic Acid—Peptide Conjugates,”Biochemistry,41(37):11118-11125 (2002).
Khan, A.U., et al., “Director Spectroscopic Observation of Singlet Oxygen Emission at 1268 nm Excited by Sensitizing Dyes of Biological Interest in Liquid Solution,”Proc Natl Acad Sci USA,76(12):6047-6049 (1979).
Kielkopf, C. L., et al., “A Structural Basis for Recognition of A-T and T-A Base Pairs in the Minor Groove of B-DNA,”Science,282(5386):111-115 (1998).
Komiyama, et al., “PNA for One-Base Differentiating Protection of DNA from Nuclease and its Use for SNPs Detection,”J Am Chem Soc,125:3758-3762 (2003).
Kuhn H., et al., “Hybridization of DNA and PNA Molecular Beacons to Single-Stranded and Double-Stranded DNA Targets,”J Am Chem Soc,124(6):1097-1103 (2002).
Lartia, et al., “New Cyanine-Oligonucleotide Conjugates: Relationships between Chemical Structures and Properties,”Chem. Eur. J.,12:2270-2281 (2006).
Larsen H., et al., “Antisense Properties of Peptide Nucleic Acid,”Biochim et Biophys Acta,1489:159-166 (1999).
Lee L., et al., “Thiazole Orange: A New Dye for Reticulocyte Analysis,”Cytometry,7:508-517 (1986).
Lion, Y., et al., “New Method of Detecting Singlet Oxygen Production,”Nature,263:442-443 (1976).
Lohse, J., et al., “Double Duplex Invasion by Peptide Nucleic Acid: A General Principle for Sequence-Specific Targeting of Double-Stranded DNA,”Proc Natl Acad Sci,96(21):11804-11808 (1999).
Lukeman P.S., et al., “Two Dimensional PNA/DNA Arrays: Estimating the Helicity of Unusual Nucleic Acid Polymers,”Chem Commun,1694-1695 (2004).
Matsui M., et al. “Synthesis and Characterization of Mono-, Bis-, and Trissubstituted Pyridinium and Pyrylium Dyes,”Bull Chem Soc Jpn,65(1):71-74 (1992).
Matysiak, S., et al., “Automating Parallel Peptide Synthesis for the Production of PNA Library Arrays,”BioTechniques,31(4):896-904 (2001).
McRae, et al., “Enhancement of Phosphorescence Ability upon Aggregation of Dye Molecules,”M J of Chem Phys,28:721-722 (1958).
Mikheikin A.L., et al., “Binding of Symmetrical Cyanine Dyes into the DNA Minor Groove,”J. Biomol. Struct. Dyn.,18(1):59-72 (2000).
M&#
Blidner Rick
Holmes-Davis Rachel Anne
Jedrzejewska Beata Anna
Koshinsky Heather
Paczkowski Jerzy
Brinks Hofer Gilson & Lione
Chunduru Suryaprabha
Investigen, Inc.
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