Assays and kits for detecting analytes in the presence of cross-

Details Assays and kits for detecting analytes in the presence of cross- Assays and kits for detecting analytes in the presence of cross-

1993-01-19

1999-06-22

Housel, James C.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving antigen-antibody binding, specific binding protein...

435 75, 435 792, 435 17, 435971, 436518, 436540, G01N 33536, G01N 33573

Patent

active

059142413

ABSTRACT:
An immunoassay is provided which is selective for an analyte over immunologically related substances which may be present in a sample to be tested. The presence of the analyte is detected using a first binding substance, typically an antibody, in the presence of a second binding substance, typically another antibody. The first binding substance recognizes an epitope which is characteristic of the analyte and cross-reacts with a related epitope on the cross-binding substance. The second binding substance preferentially binds the common epitope on the cross-binding substance, thus reducing non-specific binding of the first binding substance.

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