Assaying of polynuclear aromatic compounds

Details Assaying of polynuclear aromatic compounds Assaying of polynuclear aromatic compounds

1987-02-24

1990-01-02

Richman, Barry S.

Chemistry: analytical and immunological testing

Cancer

436 29, 436 60, 436110, 436140, 436164, 436813, G01N 3300, G01N 2100

Patent

active

048913227

ABSTRACT:
A very rapid, sensitive method if provided for determination of the potential mutagenicity and/or carcinogenicity of certain petroleum oils by nitration of the oil and comparison of the light absorbance of its nitrated material with that obtained from one or more oils of known mutagenicity and/or carcinogenicity.

REFERENCES:
Litten et al., Relationship Between Fluorescence of Polynuclear Aromatic Hydrocarbons in Complex Environmental Mixtures and Sample Mutagenicity, 1982, 28(2) 141-8.
Wehry et al., Recent Developments in Matrix Isolation Spectroscopic Analysis of Polynuclear Aromatic Hydrocarbons, 1979, 1005-23.
Robinson et al., Handbook of Spectroscopy vol. II, 1980, pp. 134-214.
Campbell et al., "Nitrated Polycyclic Aromatic . . . " Carcinogenesis, vol. 2, No. 6, 559-565.
DiPaola et al., "Nitration of Carcinogenic . . . " Carcinogenesis, vol. 4, No. 3, pp. 357-359.
Rosenkrantz et al., "Mutagenicity . . . " Mutation Research, 114 (1983), pp. 217-219.
Towkiwa et al., "1-6-Dinitropyrene: Mutagenicity . . . " JNCI, vol. 73, No. 6, Dec. 1984, pp. 1359-1363.

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