Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving luciferase
Reexamination Certificate
2006-08-22
2006-08-22
Yu, Misook (Department: 1642)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving luciferase
C435S006120, C435S325000, C435S368000, C435S370000
Reexamination Certificate
active
07094559
ABSTRACT:
The present invention relates to an assay system and method for testing compounds for their ability to regulate the hepatic lipase (HL) promoter. In particular, the invention relates to the identification of estrogen receptor ligands having this activity. Compounds that inhibit HL promoter activity are useful as leads, or on their own, to develop therapeutics in the prevention of heart disease.
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Harnish Douglas C.
Hsiao Chu-Lai
Karathanasis Sotirios K.
Scicchitano Marshall S.
Wilmer Cutler Pickering Hale and Dorr LLP
Wyeth
Yu Misook
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