Assay timed by electrical resistance change and test strip

Details Assay timed by electrical resistance change and test strip Assay timed by electrical resistance change and test strip

1993-01-13

1994-09-06

Wityshyn, Michael G.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

436 46, 436808, 422 56, C12Q 100, G01N 3500, G01N 2100

Patent

active

053447549

ABSTRACT:
Assays for liquid analytes are performed on a bibulous matrix containing dried reagents which produce a visibly detectable reaction product. Application of liquid sample to the bibulous matrix is detected by measuring a drop in resistance across the matrix. A preferred test article for performing the method includes the matrix and a pair of spaced-apart electrodes in electrical contact with a reaction zone on the matrix. The test article is used in combination with a detection unit having means for probing the electrodes to determine when electrical resistance in the matrix has decreased. The assay methods and apparatus are particularly useful for performing enzyme assays where signal developed as a function of time is critical.

REFERENCES:
patent: 3663374 (1972-05-01), Moyer et al.
patent: 3791933 (1974-02-01), Moyer et al.
patent: 3826734 (1974-07-01), Godsey
patent: 4038030 (1977-07-01), Albright et al.
patent: 4053381 (1977-10-01), Hamblen et al.
patent: 4171246 (1979-10-01), Hamblen
patent: 4219529 (1980-08-01), Tersteeg et al.
patent: 4256693 (1981-03-01), Kondo et al.
patent: 4366241 (1982-12-01), Tom
patent: 4420566 (1983-12-01), Jessop et al.
patent: 4720372 (1988-01-01), Fey et al.
patent: 4911794 (1990-03-01), Parce
patent: 4935346 (1990-06-01), Phillips et al.
patent: 5049487 (1991-09-01), Phillips et al.
patent: 5059394 (1991-10-01), Phillips et al.
patent: 5059525 (1991-10-01), Bartl et al.
Foulds N., Rapid Electrochemical Assay for Theophylline . . . Anal Chim Acta 229 (1990) pp. 57-62.

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