Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Patent
1997-09-03
2000-01-04
Prouty, Rebecca E.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
4353201, 4352523, 435325, C12Q 168, C12N 1563, C12N 121, C12N 510
Patent
active
060108568
ABSTRACT:
Assay systems utilizing a reporter construct based on p38 phosphorylation of myocyte enhancer factor 2 (MEF2) transcription factor are provided. The reporter construct and methods of use are provided, as well as methods of treatment of inflammatory and muscular disorders associated with MEF2-regulated gene expression.
REFERENCES:
J. Han et al., "Activation of the Transcription Factor MEF2C by the MAP Kinase p38 in Inflammation", Nature 386:296-299, Mar. 1997.
Y. Jiang et al., "Characterization of the Structure and Function of a New Mitogen-Activated Protein Kinase (p38.beta.)", J. Biol. Chem. 271: 17920-6, Jul. 1996.
Han Jiahuai
Jiang Yong
Li Zhuang-Jei
Ulevitch Richard J.
Fitting Thomas
Holmes Emily
Prouty Rebecca E.
The Scripps Research Institute
LandOfFree
Assay systems and methods for measuring P38 map kinase, and modu does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Assay systems and methods for measuring P38 map kinase, and modu, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Assay systems and methods for measuring P38 map kinase, and modu will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1071648