Assay of immunoglobulin A protease and the rapid diagnosis of go

Details Assay of immunoglobulin A protease and the rapid diagnosis of go Assay of immunoglobulin A protease and the rapid diagnosis of go

1981-12-23

1986-04-15

Padgett, Ben R.

Drug, bio-affecting and body treating compositions

Radionuclide or intended radionuclide containing; adjuvant...

424 87, 424 9, 435 7, 435 23, 435259, 435810, 436511, 436515, 436518, 436533, 436536, 436540, 436542, 260112R, 206569, G01N 3354, A61K 3940

Patent

active

045826994

ABSTRACT:
A method for rapid diagnosis of gonorrhea is set forth comprising assay of the enzyme immunoglobulin A protease (IgAP). Immunoassays including radioimmunoassay and enzyme-linked immunoassay with monoclonal antibodies to IgAP are disclosed. A kit for early detection of gonorrhea is given. The assay and kit of the present invention may also be used in the detection of meningitis.

REFERENCES:
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Plaut, A. G. et al., New England Journal of Medicine, vol. 298 (26), pp. 1459-1463 (1978).
Blake, M. S. et al., Infection and Immunity, vol. 22 (2), pp. 350-358 (1978).
Mulks, M. H. et al., J. Experimental Medicine, vol. 152, pp. 1442-1447 (11-1980).
Kilian, M. et al., J. Immunology, vol. 124 (6), pp. 2596-2600 (1980).
Kilian, M. et al., Infection and Immunity, vol. 26 (1), pp. 143-149 (1979).
Jabib, R. S. et al., Biochimica et Biophysica Acta, vol. 526, pp. 547-559 (1978).
Mulks, M. H. et al., J. Infectious Disease, vol. 141, (4), pp. 450-456 (1980).
Male, C. J., Infection and Immunity, vol. 26, pp. 254-261 (1979).
Blake, M. et al., J. Infectious Diseases, vol. 139, (1), pp. 89-92 (1979).
Kilian, M. et al., Infection and Immunity, vol. 31 (3), pp. 868-873 (3-1981).

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