Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Patent
1995-06-01
1998-09-01
Elliott, George C.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
C12Q 168
Patent
active
058009868
ABSTRACT:
Assays screened for compounds that inhibit tat transactivation of the HIV (HTLV-III) LTR are taught. The assay involves tranfecting a cell line containing the tat gene by a vector containing a gene under the control of an HIV-1 LTR, adding the compound to be screened and determining the effect of the compound by looking at the effect of tat as measured by the expression of the gene under the control of the HIV LTR.
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Goh Wei Chun
Haseltine William Alan
Rosen Craig A.
Sodroski Joseph Gerald
Conlin David C.
Dana Farber Cancer Institute
Eisenstein Ronald I.
Elliott George C.
McKelvey Terry A.
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