Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving virus or bacteriophage
Patent
1995-12-22
1998-06-09
Smith, Lynette F.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving virus or bacteriophage
435 71, 435 72, 435 721, 435 794, C12Q 170, G01N 3353, G01N 33567
Patent
active
057631611
ABSTRACT:
Disclosed are a method for testing for the presence of a cytomegalovirus antigen by using an antibody which specifically recognizes cytomegalovirus Lower matrix protein pp65, as a primary antibody, which comprises using an alkaline phosphatase-labeled antibody as a secondary antibody and a method for testing for the presence of a cytomegalovirus antigen which comprises using an alkaline phosphatase-labeled antibody which specifically recognizes cytomegalovirus Lower matrix protein pp65, or (Fab').sub.2 or Fab' fragment of the antibody which specifically recognizes cytomegalovirus Lower matrix protein pp65 as a primary antibody.
REFERENCES:
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Bone Marrow Transplantation, vol. 9, pp. 247-253, 1992, A.M. Vlieger, et al., "Cytomegalovirus Antigenemia Assay or PCR Can Be Used to Monitor Ganciclovir Treatment in Bone Marrow Transplant Recipients".
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Biotest Bulletin, vol. 5, pp. 63-72, 1993, G. Bein, et al., "Cytomegalovirus Infection in Transplantation Medicine. Current Diagnostic Approaches With Special Emphasis on the PP65 Antigenemia Assay".
Asai Takayoshi
Hayashi Junko
Ito Akio
Kurihara Takashi
Nelson Brett
Smith Lynette F.
Yuka Medias Co., Ltd.
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