Assay method for serum folate

Details Assay method for serum folate Assay method for serum folate

1975-11-10

1977-06-07

Scovronek, Joseph

Drug, bio-affecting and body treating compositions

Radionuclide or intended radionuclide containing; adjuvant...

Molecular bilayer structure

23230B, 232306, 2602515, C07D47500, G01N 3106, G01N 3316, G01T 116

Patent

active

040284654

ABSTRACT:
Serum folate assay procedure by competitive binding in which serum folate is stabilized while being freed from serum folate proteins in the presence of a dithiopolyol, preferably a 1,4-dithiotetritol such as dithiothreitol. Subsequently in the procedure, free folate is separated from competitively bound folate by the addition of dry dextran coated charcoal in a tablet form.

REFERENCES:
patent: 3442819 (1969-05-01), Herbert et al.
Akerkar et al., "Stability of Tritiated Folic Acid used in Radioimmunoassay", Clinical Chemistry, vol. 21, No. 7, p. 1030 (June 1975).

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