Chemistry: analytical and immunological testing – Involving an insoluble carrier for immobilizing immunochemicals – Carrier is inorganic
Patent
1987-07-06
1990-04-10
Nucker, Christine M.
Chemistry: analytical and immunological testing
Involving an insoluble carrier for immobilizing immunochemicals
Carrier is inorganic
422 68, 436805, 436806, 436807, 436518, G01N 33553
Patent
active
049160818
ABSTRACT:
An immunoassay method and apparatus includes the vibration of beads within a cell, the beads having a complex of a substance conjugated with an enzyme as a marker on the surface thereof, and using an optical measurement device to quantatively determine the amount of the marker in the cell. The vibration is provided by including a magnetic material in the beads and causing a magnetic field to move within the cell. The vibrations have at least a component transverse to a measurement direction of the optical measurement device. The movement of the magnetic field in the cell is caused by the reciprocation of a bar having magnets thereon and in a position adjacent to the cell.
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Methods in Enzymology, vol. XXXIV, "Affinity Techniques", Covalent Linkage of Functional Ligands, and Proteins to Polyacrylamide Beads, John K. Inman, pp. 30-58, 1974.
Iwasaki Shuji
Kamada Satoru
Krupen Karen I.
Nucker Christine M.
Toyo Soda Manufacturing Co. Ltd.
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