Drug – bio-affecting and body treating compositions – Radionuclide or intended radionuclide containing; adjuvant... – Molecular bilayer structure
Patent
1980-05-21
1982-10-19
Nucker, Christine M.
Drug, bio-affecting and body treating compositions
Radionuclide or intended radionuclide containing; adjuvant...
Molecular bilayer structure
23230B, 424 12, G01N 3356
Patent
active
043550185
ABSTRACT:
A highly specific assay for plasma vitamin B.sub.12 levels in humans is disclosed. The assay employs intrinsic factor preparations obtained from mouse or rat stomachs, which intrinsic factors are free of R-protein and thus react specifically with vitamin B.sub.12 in a competitive binding assay. Detection of vitamin B.sub.12 levels is utilized in the diagnosis of several clinical disorders, such as pernicious anemia, a disease state which results in reduced circulating levels of vitamin B.sub.12 in the blood.
REFERENCES:
patent: 3937799 (1976-02-01), Lewin et al.
patent: 4146602 (1979-03-01), Gutcho et al.
patent: 4188189 (1980-02-01), Allen
patent: 4209614 (1980-06-01), Bernstein et al.
Hansen Hans J.
Reynoso Gustavo
Gould George M.
Hoffmann-La Roche Inc.
Nucker Christine M.
Saxe Jon S.
The Ideal Wilson Medical Center
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