Assay for tumor necrosis factor receptor-associated factors

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid

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435 71, 435 72, 435 697, 4351723, 536 234, C12N 1562

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active

056703198

ABSTRACT:
The invention concerns new tumor necrosis factor receptor associated factors, designated TRAF. The new factors are capable of specific association with the intracellular domain of the type 2 TNF receptor (TNF-R2), and are involved in the mediation of TNF biological activities.

REFERENCES:
patent: 4861587 (1989-08-01), Urbaschek et al.
"Phosphorylated tyrosine residues are recognized by proteins with SH2 domains" Molecular Biology of The Cell, Alberts et al., Third Edition edition, New York and London:Garland Publishing, Inc. pp. 761-762 (1994).
Bazan, F., "Emerging families of cytokines and receptors" Current Biology 3(9):603-606 (1993).
Wong et al., "Antiviral activity of tumor necrosis factor (TNF) is signaled through the 55-kDa receptor, type I TNF" J. Immunol. 149(10):3350-3353 (1992).
Berg, J., "Zinc Fingers and Other Metal-Binding Domains," J. Biol. Chem. 265(12): 6513-6516 (1990).
Beutler, B. and Cerami, A., "Tumor Necrosis, Cachexia, Shock, and Inflammation: A Common Mediator," Ann. Rev. Biochem. 57, 505-518 (1988).
Blake, T. et al., "The Sequences of the Human and Mouse c-cbl Proto-Oncogenes Show v-cbl was Generated by a Large Truncation Encompassing a Proline-Rich Domain and a Leucine Zipper-Like Motif," Oncogene 6: 653-657 (1991).
Brockhaus, M. et al., "Identification of Two Types of Tumor Necrosis Factor Receptors on Human Cell Lines by Monoclonal Antibodies," Proc. Natl. Acad. Sci. USA 87, 3127-3131 (1990).
Chan, E. et al., "Molecular Definition and Sequence Motifs of the 52-kD Component of Human SS-A/Ro Autoantigen," J. Clin. Invest. 87: 68-76 (1991).
Chevray, P. et al., "Protein Interaction Cloning in Yeast: Identification of Mammalian Proteins that React with the Leucine Zipper of June," Proc. Natl. Acad. Sci. USA 89: 5789-5793 (1992).
Chien, C. et al., "The Two-Hybrid System: A Method to Identify and Clone Genes for Proteins that Interact with a Protein of Interest," Proc. Natl. Acad. Sci. USA 9578-9582 (1991).
Deng, X. et al., "COP1, an Arabiodopsis Regulatory Gene, Encodes a Protein with Both a Zinc-Binding Motif and a G.sub..beta. Homologous Domain," Cell 71: 791-801 (1992).
Driscoll and Williams, "Two Divergently Transcribed Genes of Dictyostelium Discoideum Are Cyclic AMP-Inducible and Coregulated during Development," Mol. Cell. Biol. 7(12): 4482-4489 (1987).
Engelmann, H. et al., "Antibodies to a Soluble Form of a tumor Necrosis Factor (TNF) Receptor Have TNF-Like Activity," J. Biol. Chem. 265, 14497-14504 (1990).
Espevik, T. et al., "Characterization of Binding and Biological Effects of Monoclonal Antibodies Against a Human Tumor Necrosis Factor Receptor," J. Exp. Med. 171, 415-426 (1990).
Fields and Song, "A Novel Genetic System to Detect Protein-Protein Interactions," Nature 340: 245-246 (1989).
Fiers, W., "Tumor Factor Characterization at the Molecular, Cellular and In Vivo Level," FEBS Lett. 285(2), 199-212 (1991).
Goeddel, D.V. et al., "Tumor Necrosis Factors: Gene Structure and Biological Activities," Cold Spring Harbor Symposia on Quantitative Biology 51, 597-609 (1986).
Goodwin, R.G. et al., "Molecular Cloning and Expression of the Type 1 and Type 2 Murine Receptors for Tumor Necrosis Factor," Mol. Cell. Biol. 11, 3020-3026 (1991).
Gray et al., "Cloning and Expression of cDNA for Human Lymphotoxin, A Lymphokine with Tumor Necrosis Activity," Nature 312, 724 (1984).
Hohmann et al., "Expression of the Types A and B Tumor Necrosis Factor (TNF) Receptors Is Independently Regulated, and Both Receptors Mediate Activation of the Transcription Factor NF-kB," J. Biol. Chem. 265, 22409-22417 (1990).
Hohmann, H.P. et al., "Two Different Cell Types Have Different Major Receptors for Human Tumor necrosis Factor (TNF.alpha.)," J. Biol. Chem. 264, 14927-14934 (1989).
Inoue, S. et al., "Genomic Binding-Site Cloning Reveals an Estrogen-Responsive Gene that Encodes a RING Finger Protein," Proc. Natl. Acad. Sci. USA 90: 11117-11121 (1993).
Itoh, K. et al., "Protein Heterogeneity in the Human Ro/SSA Ribonucleoproteins," J. Clin. Invest. 87: 177-186 (1991).
Jones, J. et al., "The Saccharomyces Cerevisiae RAD18 Gene Encodes a Protein that Contains Potential Zinc Finger Domains for Nucleic Acid binding and a Putative Nucleotide Binding Sequence," Nucl. Acids Res. 16(14): 7119-7131 (1988).
Kohno, T. et al., "A Second Tumor Necrosis Factor Receptor Gene Product Can Shed a Naturally Occurring Tumor Necrosis Factor Inhibitor," Proc. Natl. Acad. Sci. U.S.A. 87, 8331 (1990).
Lenardo & Baltimore, "NF-kB: A Pleiotropic Mediator of Inducible and Tissue-Specific Gene Control," Cell 58: 227-229 (1989).
Lewis, M. et al., "Cloning and Expression of cDNAs for Two Distinct Murine Tumor Necrosis Factor Receptors Demonstrate One Receptor is Species Specific," Proc. Natl. Acad. Sci. USA 88, 2830-2834 (1991).
Loetscher, H. et al., "Molecular Cloning and Expression of the Human 55 kd Tumor Necrosis Factor Receptor," Cell 61, 351 (1990).
Mardon and Page, "The Sex-Determining Region of the Mouse Y Chromosome Encodes a Protein with a Highly Acidic Domain and 13 Zinc Fingers," Cell 56: 765-770 (1989).
Miller, J. et al., "Repetitive Zinc-Binding Domains in the Protein Transcription Factor IIIA from Xenopus Oocytes," EMBO J. 4(6): 1609-1614 (1985).
Miyatake et al., "Structure of the Chromosomal Gene for Granulocyte-Macrophage Colony Stimulating Factor: Comparison of the Mouse and Human Genes," EMBO J. 4: 2561-2568 (1985).
Naume, B. et al., "Involvement of the 55-and 75-kDA tumor Necrosis Factor Receptors in the Generation of Lymphokine-Activated Killer Cell Activity and Proliferation of Natural Killer Cells," J. Immunol. 146, 3035-3048 (1991).
Neta et al., "Interleukin 1 is a Radioprotector" J. Immunol. 136(7): 2483-2485, (1987).
Neta et al., "Comparison of the In Vivo Effects of rIL-1 and rTNF in Radioprotection, Induction of CSF and of Acute Phase Reactants," Fed. Proc. 46: 1200 (abstract), (1987).
Neta et al., "Interdependence of the Radioprotective Effects of Human Recombinant Interleukin 1.alpha., Tumor Necrosis Factor .alpha., Granulocyte Colony-Stimulating Factor, and Murine Recombinant Granulocyte-macrophage Colony-Stimulating Factor," J. Immunol. 140: 108-111 (1988).
Nietfeld, T. et al., "Second-Order Repeats in Xenopus Laevis Finger Proteins," J. Mol. Biol. 208: 639-659 (1989).
Nophar, Y. et al., "Soluble Forms of Tumor Necrosis Factor Receptors (TNF-Rx). The cDNA for the Type I TNF-R, Cloned Using Amino Acid Sequence Data of Its Soluble Form, encodes both the Cell Surface and a Soluble Form of the Receptor," EMBO J. 9, 3269-3278 (1990).
Old, L.J., "Tumor Necrosis Factor," Sci. Am. 258(5), 59-75 (1988).
Opipari et al., "The A20 cDNA Induced by Tumor Necrosis Factor .alpha. Encodes a Novel Type of Zinc Finger Protein",: J. Biol. Chem. 265: 14705-14708 (1990).
Patarca R. et al., "rpt-1, An Intracellular Protein from Helper/Inducer T Cell that Regulates Gene Expression of Interleukin 2 Receptor and Human Immunodeficiency Virus Type 1," Proc. Natl. Acad. Sci. USA 85: 2733-2737 (1988).
Pennica et al., "Human Tumour Necrosis Factor: Precursor Structure, Expression and Homology to Lymphotoxin," Nature 312, 721 (1984).
Ruiz i Altaba, A. et al., "Xfin: An Embryonic Gene Encoding a Multifingered Protein in Xenopus," EMBO J. 6(10): 3065-3070 (1987).
Schall, T.J. et al., "Molecular Cloning and Expression of a Receptor for Human Tumor Necrosis Factor," Cell 61, 361-370 (1990).
Schatz, D. et al., "The V(D)J Recombination Activating Gene, RAG-1," Cell 59: 1035-1048 (1989).
Shalaby, M.R. et al., "Binding and Regulation of Cellular Functions by Monoclonal Antibodies against Human Tumor Necrosis Factor Receptors," J. Exp. Med. 172, 1517-1520 (1990).
Smith, C.A. et al., "A Receptor for Tumor Necrosis Factor Defines an Unusual Family of Cellular and Viral Proteins," Science 248, 1019 (1990).
Stanley et al., "The Structure and Expression of the Murine Gene Encoding Granulogyte-Macrophage Colony Stimulating Factor: Evidence for Utilisation of Alternative Promoters," EMBO J. 4: 2569-2573 (1985)).
Takahashi, M. et al., "Developmentally Regulated Expression of a Human Finger-Containing Gene Encoded by the 5

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