Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Patent
1989-08-28
1992-06-02
Ceperley, Mary E.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
435 792, 435 794, 435 795, 435810, 436 93, 436518, 436527, 436538, 436544, 436545, 436546, 436800, 436804, 436805, 436808, 436815, 436822, 436825, G01N 33543, G01N 33534
Patent
active
051186128
ABSTRACT:
An immunoassay for trichothecenes that have at least three hydroxyl groups at specified positions is disclosed. It relies on developing antibodies to close trichothecene variants that are missing at least one of the hydroxyl groups, and then using these antibodies to test specimens in which the trichothecene has been converted to the variant (usually to the OAC variant). For example, DON and T-2 tetraol can be assayed for using this invention.
REFERENCES:
patent: 4744981 (1988-05-01), Pavanasasivam
patent: 4772551 (1988-09-01), Hart et al.
patent: 4906452 (1990-03-01), Sivam
H. Kemp et al., 37, J. Sci. Food Agric., 888-894 (1986).
T. Fan et al., 47, J. Food Prot., 964-967 (1984).
J. Pestka et al., 940A-944A, JAOCS (1981).
S. Lee et al., 72, Tox. Appl. Pharm., 228-235 (1984).
F. Chu et al., 37, Appl. Environ. Micro., 104-108 (1979).
G. Zhang et al., 51, Appl. Environ. Micro., 132-137 (1986).
R. Wei et al., 49, J. Food Prot., 267-271 (1986).
F. Chu et al., 48, Appl. Environ. Micro., 781-784 (1984).
R. Vesonder et al., 16, Process Biochem., 12-15 (1980).
G. Bennett et al., 58, J. Am. Oil Chem. Soc., 1002A-1005A (1981).
K. Ehrlich et al., 48, Microbiology, 1053-1054 (1984).
F. Chu et al., 48, Appl. Environ. Micro., 777-780 (1984).
F. Chu, Mycotoxins and Phycotoxins, P. S. Steyn and R. Vleggaar, (Eds), 277-292 (1985).
F. Chu, 47, J. Food Prot., 562-569 (1984).
Yoshizawa et al., 46, Agric. Biol. Chem., 2613-2615 (1982).
Wei et al., 45, Biochem. Biophys. Res. Comm., 396-401 (1971).
Wallace et al., 25, J. Ag. Fd. Chem., 836-838 (1977).
G. Zhang et al., 49, J. Food Prot., 336-339 (1986).
Y. Xu et al., 69, J. Assoc. Off. Anal. Chem., 967-969 (1986).
R. Wei et al., 160, Anal. Biochem., 399-408 (1987).
T. Fan et al., 53, Appl. Environ. Micro., 17-21 (1987).
Chu Fun S.
Wei Ru-Dong
Zhang Guang S.
Ceperley Mary E.
Wisconsin Alumni Research Foundation
LandOfFree
Assay for trichothecenes does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Assay for trichothecenes, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Assay for trichothecenes will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2228064